Malleable ribonucleoprotein machine: protein intrinsic disorder in theSaccharomyces cerevisiaespliceosome
نویسندگان
چکیده
منابع مشابه
Malleable ribonucleoprotein machine: protein intrinsic disorder in the Saccharomyces cerevisiae spliceosome
Recent studies revealed that a significant fraction of any given proteome is presented by proteins that do not have unique 3D structures as a whole or in significant parts. These intrinsically disordered proteins possess dramatic structural and functional variability, being especially enriched in signaling and regulatory functions since their lack of fixed structure defines their ability to be ...
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2 The dominant view of protein structure-function is that an amino acid sequence specifies a (mostly) fixed three-dimensional (3-D) structure that is a prerequisite to protein function. In contrast to the dominant view, many proteins display functions requiring the disordered state. Our purpose here is to provide a catalogue of disorder-function relationships. The very important molecular detai...
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ژورنال
عنوان ژورنال: PeerJ
سال: 2013
ISSN: 2167-8359
DOI: 10.7717/peerj.2